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What (who) is pyridine sulfonamide - definition
CHEMICAL COMPOUND
Pyridine-sulfur trioxide; C5H5NSO3
sulphonamide
![[[Saccharin]], a cyclic sulfonamide that was one of the first [[artificial sweeteners]] discovered.](https://commons.wikimedia.org/wiki/Special:FilePath/Saccharin.svg?width=200 "[[Saccharin]], a cyclic sulfonamide that was one of the first [[artificial sweeteners]] discovered.")
![[[Sulfanilamide]], a compound that foreshadowed the development of sulfa drugs.](https://commons.wikimedia.org/wiki/Special:FilePath/Sulfanilamide-skeletal.svg?width=200 "[[Sulfanilamide]], a compound that foreshadowed the development of sulfa drugs.")
![[[Sulfamethoxazole]] is a widely used [[antibiotic]].](https://commons.wikimedia.org/wiki/Special:FilePath/Sulfamethoxazole-skeletal.svg?width=200 "[[Sulfamethoxazole]] is a widely used [[antibiotic]].")
![[[Ampiroxicam]] is a sultam used as an antiinflammatory drug.](https://commons.wikimedia.org/wiki/Special:FilePath/Ampiroxicam int.svg?width=200 "[[Ampiroxicam]] is a sultam used as an antiinflammatory drug.")
![[[Hydrochlorothiazide]] is a drug that features both acyclic and cyclic sulfonamide groups.](https://commons.wikimedia.org/wiki/Special:FilePath/Hydrochlorothiazide-2D-skeletal.png?width=200 "[[Hydrochlorothiazide]] is a drug that features both acyclic and cyclic sulfonamide groups.")
![[[Camphorsultam]] is a sultam used as a [[chiral auxiliary]] in organic synthesis.](https://commons.wikimedia.org/wiki/Special:FilePath/Oppolzer sultam.svg ?width=200 "[[Camphorsultam]] is a sultam used as a [[chiral auxiliary]] in organic synthesis.")
CLASS OF CHEMICAL COMPOUNDS
Sulphonamides; Sulphonamide; Sulphonamide (chemistry); Sulfonamide (chemistry); Sulfonamides; Sultam
Sulfonamide
CLASS OF CHEMICAL COMPOUNDS
Sulphonamides; Sulphonamide; Sulphonamide (chemistry); Sulfonamide (chemistry); Sulfonamides; Sultam
In chemistry, the sulfonamide functional group (also spelled sulphonamide) is -S(=O)2-NH2, a sulfonyl group connected to an amine group. Relatively speaking this group is unreactive.
sulpha
![[[Furosemide]] is a sulfonamide, but not a thiazide.](https://commons.wikimedia.org/wiki/Special:FilePath/Furosemide.svg?width=200 "[[Furosemide]] is a sulfonamide, but not a thiazide.")
![PABA]] (center) is the basis for the inhibitory activity of sulfa drugs on tetrahydrofolate (right) biosynthesis.](https://commons.wikimedia.org/wiki/Special:FilePath/Sulfa folate.svg?width=200 "PABA]] (center) is the basis for the inhibitory activity of sulfa drugs on tetrahydrofolate (right) biosynthesis.")
CLASS OF PHARMACEUTICAL DRUGS
Sulfa Drugs; Sulfa drugs; Sulfa; Sulpha; Sulfa drug; Sulfa powder; Sulphonamide (medicine); Sulpha drugs; Sulpha drug; Sulfa antibiotic; Sulfonamide antibiotics; Sulfonamide allergy; Sulfa allergy
Wikipedia
Sulfur trioxide pyridine complex
Sulfur trioxide pyridine complex is the compound with the formula C5H5NSO3. It is a colourless solid that dissolves in polar organic solvents. It is the adduct formed from the Lewis base pyridine and the Lewis acid sulfur trioxide. The compound is mainly used as a source of sulfur trioxide, for example in the synthesis of sulfate esters from alcohols:
- ROH + C5H5NSO3 → [C5H5NH]+[ROSO3]−
It also is useful for sulfamations:
- R2NH + C5H5NSO3 → C5H5N + R2NSO3H
The compound is used for sulfonylation reactions, especially in the sulfonylation of furans. It is also an activating electrophile in a Parikh-Doering oxidation.
